Pre-registered RCT

Found Health × COYL. Interim data.

A pre-registered randomized trial of behavioral-interrupt protocol vs. standard care across GLP-1-active adults. This page is the public ledger — pre-registered before recruitment, updated as interim data lands.

Last updated . Pre-registered 2026-04-15. Study ID COYL-FH-001.

01 · Pre-registered design

What we said we'd measure. Before recruitment opened.

Population

GLP-1-active adults, 18–65, English-speaking, US residents

Arms

Intervention

COYL behavioral-interrupt protocol via iOS + web. Danger-window-aware notifications, same-night recovery flow, weekly archetype digest.

Control

Standard Found Health care + non-personalized weekly behavioral-health email (sham contact-time control).

Primary endpoint

Slip-recovery rate at 30 days — % of logged autopilot-loop slips that complete the same-night stabilization protocol within 24 hours.

Secondary endpoints

  • D7 retention (% active in days 0–7)
  • D30 retention (% active in days 14–30)
  • Streak integrity at 30 days (% of streaks > 1 with grace-window survival vs. legacy reset behavior)
  • Excuse-category frequency change (baseline → week 4)

Exclusion

Active eating disorder per DSM-5; current substance-use crisis; <30 days from any major mental-health event. Routed to crisis services per the /safety policy.

IRB status

IRB-exempt (minimal-risk behavioral)

02 · Results

What we've measured. Or haven't yet.

Every endpoint below is pre-registered above. PENDING rows convert to INTERIM as data locks. INTERIM converts to FINAL on study completion. No post-hoc additions on this page.

PENDING

Primary endpoint

Slip-recovery rate at 30 days — % of logged autopilot-loop slips that complete the same-night stabilization protocol within 24 hours.

Interim readout pre-registered for the 60-day data lock. Awaiting cohort completion of the recruitment window.

Recruiting

PENDING

Secondary endpoint

D7 retention

D7 cohort active. Numbers post once the first wave passes day 14 in study.

PENDING

Secondary endpoint

D30 retention

D30 cohort active. Numbers post on the 60-day interim window.

PENDING

Secondary endpoint

Streak integrity at 30 days

Numerator: streaks that survived ≥1 missed day via grace window. Denominator: all streaks > 1 in the study cohort.

PENDING

Secondary endpoint

Excuse-category frequency change

Baseline-to-week-4 delta per ExcuseCategory enum (8 categories). Reported as cohort distribution shift, not individual.

03 · The honesty frame

What we publish, what we don't, and what we do with a null result.

Positive interim — publish immediately. Methods, data, p-values, all of it. We trade speed for transparency every time.

Null interim— we keep the trial running and publish the null as a separate methodology proof point. Most behavioral RCTs come back null at p<0.05 on first read. That's expected. A pre-registered null with clean methodology is still rigor — and we don't hide it.

Underpowered— we extend the timeline and renegotiate cohort size with the Found Health PI. Documented here as “cohort enrollment ongoing” with the new target N.

Trial halt — published with reason. The page does not silently disappear.

04 · Partner with us on the next study

Clinics, telehealth providers, payers.

We're actively scoping a second arm. GLP-1 discontinuation relapse-prevention is the highest-leverage next study. If you have a patient population and an IRB pathway, we have the protocol and the instrumentation.